Hypersensitivity to betalactam antibiotics: a three years characterization of an Immunoallergy Outpatients' Hospital
نویسندگان
چکیده
Methods Retrospective analysis of clinical files and results of skin testing and DPT (drug provocation tests) from January 2011 to December 2013. All patients were studied according to standardized diagnostic procedures of ENDA/EAACI: serum sIgE (specific IgE) (ImmunoCAP, ThermoFisher) to penicillin G/V, amoxicillin and ampicillin; skin prick and IDT (intradermal tests) to PPL/MD (DAP, Diater), penicillin G, amoxicillin and cefuroxime with immediate and delayed reading. Other penicillin derivatives/cephalosporins were tested if they were the culprit drug. DPT with culprit drug was performed if previous investigation was negative. In confirmed cases an alternative BL was tested.
منابع مشابه
Drug provocation tests to betalactam antibiotics: experience in a paediatric setting.
BACKGROUND Few studies have been performed in children with suspected betalactam allergy. We aimed to assess the role of the drug provocation test (DPT) with betalactams in a paediatric setting and to study the association between allergy to betalactam antibiotics and other allergic diseases. METHODS We included all the patients under 15 years old who were consecutively referred to the Immuno...
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